Images: What Does DRESS Look Like DRESS Syndrome Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Pediatric EM Morsels Large, Spreading Rash After Illness Clinical Advisor DRESS Syndrome Rare Acute Dermatologic Emergency DRESS Syndrome symptoms vary by person. Reactions often occur in 2 stages: Early Reaction (like fever, rash, & enlarged lymph nodes) & Progressive Reaction (like peeling skin, facial swelling, & affected organs). DRESS Syndrome Rixis Dermatology