L Carnitine in Drosophila: A Review Carnitine in Mitochondrial Fatty Acid Transport and Oxidation Encyclopedia MDPI Combined metabolic activators to treat mitochondrial dysfunction Mitochondrial dysfunction is a common feature of many human diseases and is emerging as a therapeutic target. Systems biology and multiomics approaches have revealed that Carnitine is an essential cofactor for transport of long chain fatty acids into mitochondria, where oxidation takes place. Carnitine deficiency leads to depressed mitochondrial oxidation of fatty acids, resulting in storage of fat L carnitine Transports Fat Molecules into the Mitochondria Stock Vector Illustration of isolated, energy: 89260659 The carnitine system and cancer metabolic plasticity Cell Death & Disease