PDF] Evidence that Increased Acetaminophen use in Genetically Vulnerable Children Appears to be a Major Cause of the Epidemics of Autism, Attention Deficit with Hyperactivity, and Asthma Semantic Scholar NAPQI an overview ScienceDirect Topics N Acetyl 4 benzoquinone imine (NAPQI, N Acetyl p benzoquinonimine, CAS Number: 50700 49 7) Cayman Chemical Acetaminophen (Paracetamol) Toxicity A common and potentially fatal cause of acute liver failure due to toxic accumulation of the metabolite NAPQI when glutathione stores are depleted. Early recognition and timely administration Biotransformation, Elimination and Bile Acid Metabolism Abdominal Key