Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black Glutathione production and turnover in RBC. Schematically presented are Download Scientific Diagram Glutathione Synthetase an overview ScienceDirect Topics Response of Human Red Blood Cells to Acute and Chronic Oxidant Challenge as Observed Through the Glutathione and Glutathionyl Hemoglobin Redox Pairs In Vitro and In Vivo