Mechanism of action of statins with special reference to the lipophilic Download Scientific Diagram Personalized statin therapy: Targeting metabolic processes to modulate the therapeutic and adverse effects of statins: Heliyon One Year Effects of High Intensity Statin on Bioactive Lipids: Findings From the JUPITER Trial Arteriosclerosis, Thrombosis, and Vascular Biology Statins lower lipid levels by inhibiting HMG CoA reductase, the rate limiting enzyme in cholesterol synthesis. They're vital for reducing the risk of cardiovascular events like strokes, heart attacks, and peripheral vascular disease. Cholesterol Frontiers Pharmacogenetics of Statin Induced Myotoxicity Statin Induced Geranylgeranyl Pyrophosphate Depletion Promotes Ferroptosis Related Senescence in Adipose Tissue