In G6PD deficiency (XR), we have increased oxidative damage to RBCs, leading to intravascular hemolysis with decreased serum haptoglobin. We have decreased NADPH production, which means decreased conversion of oxidized ( S S ) glutathione Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black Mini MCAT passage: Pentose phosphate pathway and G6DP deficiency (practice) Khan Academy glucose pathways and G6PD Caspershire Meta How to Check Your Genetic Data for G6PD Deficiency PDF] 17 Glucose 6 Phosphate Dehydrogenase Defi ciency Semantic Scholar