Measuring the rate of NADPH consumption by glutathione reductase in the cytosol and mitochondria PLOS One Determination of Reduced and Total Glutathione Content in Extremophilic Microalga Galdieria phlegrea Reductive Stress Causes Oxidative Stress (Take 2) Fire In A Bottle Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Hexose Monophosphate Pathway or Pentose Phosphate Pathway Animations PharmaXChange.info 9. Oxidative Stress SimpleMed Learning Medicine, Simplified