Klotho Deficiency Causes Heart Aging via Impairing the Nrf2 GR Pathway Circulation Research Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Glutathione: What It Is, Why You Need It, How You Can Increase It The Amino Company Glutathione is indeed the master antioxidant and is found in every cell in the body. It is made from the amino acids glycine, cysteine, and glutamic acid. . One unique thing Glutathione depletion induces oxidative injury and apoptosis via TRPM2 channel activation in renal collecting duct cells ScienceDirect Chronic Glutathione Depletion Confers Protection against Alcohol induced Steatosis: Implication for Redox Activation of AMP activated Protein Kinase Pathway Scientific Reports