Pigmented lesions of the oral mucosa and perioral tissues: a flow chart for the diagnosis and some recommendations for the management ScienceDirect Oral Melanotic Macule: Symptoms and Treatment Skinsight Smoker's melanosis Wikipedia Pigmented Lesions of the Oral Mucosa Springer Nature Link Labial melanotic macule. B). Increased numbers of me lanocytes along Download Scientific Diagram This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips.