Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a Pharmacological Activation of the Melanocortin System Limits Plaque Inflammation and Ameliorates Vascular Dysfunction in Atherosclerotic Mice Arteriosclerosis, Thrombosis, and Vascular Biology Can You Take Too Much Melanotan? A Z Guide Oral pigmented lesions: a pragmatic approach to diagnosis and management Faculty Dental Journal Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in smokers, after SYNTHETIC MELANOTROPIC PEPTIDE INITIATES ERECTIONS IN MEN WITH PSYCHOGENIC ERECTILE DYSFUNCTION: DOUBLE BLIND, PLACEBO CONTROLLED CROSSOVER STUDY Journal of Urology