L Carnitine Injection VolusiaMedicalCenter IM vs SubQ Injections Olympia Pharmaceuticals Are some methods of administering HRT inherently better than others? Audience requested: subcutaneous injections. Subcutaneous means under the skin. In this type of injection, a short needle is used to inject medication Intramuscular Syringes (30 ct.) IV Me Now FL Intramuscular vs. Subcutaneous Injections: What's the Difference? Intramuscular (IM) shots go deep into the muscle for faster absorption, while subcutaneous (SubQ) injections are placed just under the skin for slower, more sustained Subcutaneous Injection Sites and Instructions for Safe Self Administration