Tylenol uses up the liver's stores of GLUTATHIONE. Glutathione is the body's most important ANTIOXIDANT. Frontiers Acetaminophen: Beyond Pain and Fever Relieving The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism William Parker, Chi Dang Hornik, Staci Bilbo, Zoie E. Holzknecht, Lauren Gentry, g glutamyl cycle. Depletion of glutathione by acetaminophen leads to Download Scientific Diagram Serotonin Deficiency Exacerbates Acetaminophen Induced Liver Toxicity In Mice Scientific Reports A new study out of John Hopkins University, funded by the NIH was just released citing that the use of Acetaminophen (Tylenol) during pregnancy increases the risk of ADHD and Autism