Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding of the differential Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a Pigmented Lesions of the Oral Mucosa Springer Nature Link Oral Melanotic Macule: Symptoms and Treatment Skinsight Oral pigmented lesions: a pragmatic approach to diagnosis and management Faculty Dental Journal