Oral pigmentation in children: a diagnostic challenge Archives of Disease in Childhood Freckle on Lip: Meaning, Causes and Is It Dangerous? (Labial Melanotic Macule) La Bouche Parfaite Oral Malignant Melanoma Oral Cancer Foundation Information and Resources about Oral Head and Neck Cancer Labial melanotic macule Metastatic oral malignant melanoma transformed from pre existing pigmented lesions in mandibular gingiva: Report of an unusual case ScienceDirect Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.