Annals of B Pod Acetaminophen Overdose Taming the SRU Sex differences in glutathione metabolism and acetaminophen toxicity Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury Vliegenthart 2017 Clinical Pharmacology & Therapeutics Wiley Online Library Paracetamol (Acetaminophen) hepatotoxicity and its management.