Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst British Journal of Haematology Wiley Online Library Frontiers Recent findings in the regulation of G6PD and its role in diseases Potential positive feedback loop involving the pentose phosphate Download Scientific Diagram Clinical associations and potential cellular mechanisms linking G6PD deficiency and atherosclerotic cardiovascular disease npj Metabolic Health and Disease Glucose 6 Phosphate Dehydrogenase an overview ScienceDirect Topics