Peptides are often well tolerated, but they can still cause temporary reactions while the body adapts. Some commonly reported effects include: BPC 157 headaches, nausea, increased appetite TB 500 CJC 1295 Ipamorelin Peptide Injections CMD CJC 1295 & Ipamorelin Guide: Benefits, Dosage, & Side Effects Sermorelin vs CJC 1295 Ipamorelin: Why Modern Medical Clinics Have Moved to the Stack Perfect B What are the downsides of Ipamorelin? Florida Surgery & Weight Loss Center Peptide side effects no one talks about BPC 157 headaches. TB 500 fatigue. CJC Ipamorelin water retention. Most people quit. But 90% of the time it's the protocol, not the peptide.