Frontiers Catalpol promotes hippocampal neurogenesis and synaptogenesis in rats after multiple cerebral infarctions by mitochondrial regulation: involvement of the Shh signaling pathway Dihexa shows neurotrophic activity exceeding BDNF in preclinical studies Alpha BioMed posted on the topic LinkedIn Dihexa Wikipedia Lately I've been getting a lot of questions about cognitive support so I started testing a few things myself. One that's stood out is Dihexa, a peptide that works at the level Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Dihexa Peptide Therapy Cognitive & Brain Function TX