Oral Melanotic Macule: Symptoms and Treatment Skinsight Oral melanotic macule Stock Image C067 2477 Science Photo Library ORAL MELANOTIC MACULE (OMM) (Also called focal melanosis labial melanotic macule) A benign, localized, flat pigmented lesion of the oral mucosa Caused by a focal increase in melanin production Oral Melanotic Macule MEDizzy What Caused These Multiple Hyperpigmented Macules of the Mouth? Oral melanotic macule and primary oral malignant melanoma: Epidemiology, location involved, and clinical implications Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics