Mechanisms of Hepatocyte Detoxification Abdominal Key Alcohol and paracetamol are both processed through the liver. Paracetamol can form a toxic metabolite called NAPQI, which the body usually neutralises safely. But factors like heavy alcohol use, repeated dosing, fasting, Solved The stepwise mechanism below shows how glutathione Chegg.com What Are the Potential Sites of Protein Arylation by N Acetyl p benzoquinone Imine (NAPQI)? Chemical Research in Toxicology Interaction with Ethanol Alcohol Metabolism Acetaminophen NAPQI Toxicity RK.MD