G6PD Deficiency causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione ( Glucose 6 phosphate dehydrogenase (G6PD) deficiency Metabolism: The pentose phosphate pathway and G6PD deficiency (practice) Khan Academy Clinical associations and potential cellular mechanisms linking G6PD deficiency and atherosclerotic cardiovascular disease npj Metabolic Health and Disease Management of Athletes With G6PD Deficiency: Does Missing an Enzyme Mean Missing More Games? Shane N. Stone, Karl V. Reisig, Heather L. Saffel, Christopher M. Miles, 2020 HEMOLYTIC ANEMIA