Mucosal melanocytic macules Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in smokers, after LABIAL LENTIGO, Labial Lentigo also called a labial melanotic macule, is a harmless, small, flat, brown spot on the lip. It can develop after repeated sun exposure. In most cases, labial lentigo Labial melanotic macules in atopic dermatitis. (a) Multiple macular Download Scientific Diagram Pathology Outlines Melanotic macule Oral Pigment lesions My Doctors