This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips. Pigmented Lesions of the Oral Mucosa Springer Nature Link Best Lip Pigmentation Treatment 2026 Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Labial melanotic macule Labial lentigines, also called labial melanotic macules, is a benign skin condition that is more common in individuals with darker skin. They most often appear during adulthood although they can develop at