About Acetaminophen Overdose A Possible Antidote for Tylenol (Paracetamol) Overdose American Council on Science and Health Why patients taking enzyme Inducers and patients with anorexia nervosa experience higher risk of paracetamol toxicity?? Acetaminophen (Paracetamol) is extensively metabolized by the liver via three main hepatic pathways: glucuronidation, sulfation, A) The CID pathways of N acetyl p benzoquinone imine glutathione Download Scientific Diagram What does NAPQI stand for? 3 Glutathione Rescue Normally, glutathione binds NAPQI and converts it into non toxic byproducts (cysteine + mercapturic acid) that are excreted. Example: Glutathione is your liver's safety net against toxins.