Vitamin B12 and ulcerative colitis: Links and more Mirikizumab can now be used to treat Crohn's Disease. Previously, this biologic medicine was used to treat Ulcerative Colitis. But, in June, the National Institute for Health and Care Excellence (NICE), approved Learn About STELARA (ustekinumab) for Ulcerative Colitis STELARA (ustekinumab) Crohn disease InDepth Inflammatory Bowel Disease (IBD): Ulcerative Colitis vs Crohn Disease IBD consists of chronic, immune mediated inflammatory disorders of the gastrointestinal tract, primarily ulcerative colitis and Crohn disease. Ulcerative Colitis (UC) Location Don't Delay Ulcerative Colitis Treatment Granite Peaks Gastroenterology