How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin The glycyl l histidyl l lysine Cu2+ tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6 ScienceDirect NL GHK Cu in the nervous system Synthagen PL The GHK Cu delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF 16 SKN 1 pathways Biogerontology Springer Nature Link Liposomal Copper GHK Oral Peptide Intermediate Cu(II) Thiolate Species in the Reduction of Cu(II)GHK by Glutathione: A Handy Chelate for Biological Cu(II) Reduction Inorganic Chemistry