Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips. Pigmented Lesions of the Oral Mucosa Pocket Dentistry Skin Cancer Warning Signs Associated Dermatology & Skin Cancer Clinic This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360