Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione. Mast cell Wikipedia Lipid orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts: Immunity The Role of Mast Cells in Health and Disease: Part 1 Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione. Ask the Expert: Your top questions about Genoskin's mast cell platform answered Genoskin