Pigmented Lesions of the Oral Mucosa: Clinical Presentation, Histology, and Recommendations for Management American Journal of Clinical Dermatology Springer Nature Link Labial melanotic macule. B). Increased numbers of me lanocytes along Download Scientific Diagram Amelanotic Melanoma Pictures Despite the name "melanosis," the pigment isn't melanin. The Pigment: It is actually lipofuscin, a "wear and tear" pigment. The Process: Anthraquinone laxatives cause apoptosis (cell death) of the colonic epithelial cells. Oral melanotic macula on the lower labial vestibular mucosa on a Download Scientific Diagram Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a