Melanotan II A Sun Kissed Look, and a Confident You. Risks of Melanotan: TGA to issue fresh warning against 'Barbie drug' The Australian What is Melanotan II the drug that the TGA urges consumers to avoid? Your body already makes a hormone that tells your skin to tan. Melanotan 2 is a synthetic peptide engineered to mimic that hormone but in a version that's more potent and No, you don't need the 'Barbie drug' to tan, whatever TikTok says. Here's why melanotan II is so risky A new viral beauty habit that could have "catastrophic" long term consequences.