Sex differences in glutathione metabolism and acetaminophen toxicity Acetaminophen Pathway (toxic doses), Pharmacokinetics Acetaminophen, also known as Tylenol, is used to help with pain & to reduce fever. However, taking too much acetaminophen can be harmful to the liver which filters out toxins & Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors