Metabolism of acetaminophen (paracetamol) in plantstwo independent pathways result in the formation of a glutathione and a glucose conjugate Environmental Science and Pollution Research Springer Nature Link 3 Glutathione Rescue Normally, glutathione binds NAPQI and converts it into non toxic byproducts (cysteine + mercapturic acid) that are excreted. Example: Glutathione is your liver's safety net against toxins. Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury Vliegenthart 2017 Clinical Pharmacology & Therapeutics Wiley Online Library Pharmacokinetic profile of metabolites by heart cutting two dimensional liquid chromatography: A focus on paracetamol analysis ScienceDirect Phase II Glutathione Conjugation Metabolism of Herbicides or Xenobiotics in Plants passel Sulfate conjugation of acetaminophen. Download Scientific Diagram
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