Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update color 43 What Caused These Multiple Hyperpigmented Macules of the Mouth? Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Oral melanotic macules are harmless but can be removed easily with laser treatment! Quick, safe, and effective. Say hello to even toned lips! #laser #candela #pico #lips #face #makeup #spa Congenital Melanocytic Macule of the Tongue in a Newborn Cureus