Carnitine Shuttle and Fatty Acid Transport Into Mitochondria The Role of l Carnitine in Mitochondria, Prevention of Metabolic Inflexibility and Disease Initiation The mechanism by which long chain fatty acids enter the mitochondria. Download Scientific Diagram Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine Carnitine transport and fatty acid oxidation ScienceDirect Carnitine metabolism in hypertensive heart failure Hypertension Research