Replenishment of Glutathione Levels Improves Mucosal Function in Experimental Acute Colitis Laboratory Investigation Glutathione Benefits & Side Effects When Should You Take Glutathione? Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Elevated serum glutathione reflects endoscopic disease activity in inflammatory bowel disease ScienceDirect JPP No 5 2016 article 08 Oral delivery of Ebselen nanoparticle modulating macrophage polarization for ulcerative colitis treatment: Cell Biomaterials