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Acetaminophen & the kidney Renal Fellow Network Unveiling the molecular basis of paracetamol induced hepatotoxicity: Interaction of N acetyl p benzoquinone imine with mitochondrial succinate dehydrogenase ScienceDirect Pharmacology 401 k Paracetamol NAPQI Glutathione COX3 Poisoning Antidote AcetylCysteine YouTube 3 Glutathione Rescue Normally, glutathione binds NAPQI and converts it into non toxic byproducts (cysteine + mercapturic acid) that are excreted. Example: Glutathione is your liver's safety net against toxins. Simplified scheme of APAP metabolism, leading to the formation of NAPQI Download Scientific Diagram Solved The stepwise mechanism below shows how glutathione Chegg.com
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napqi glutathione File:Acetaminophen metabolism.jpg
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