Autism: The Role of MTHFR and COMT Dr. Michael Veselak, D.C., CFMP MTHFR MTHFR Why is there so much interest in this gene? [JULY 2020] The MTHFR gene mutation is the world's biggest translation problem. If you're born with it, your body can't understand the language of standard vitamins. Even if you ingest them, they'll pass through, The detox gene (MTHFR) is rendered inactive when your diet is high in meat. Our diet should be 80% plant based or higher. Is The MTHFR Gene Affecting Your Health? OC Integrative Medicine