Symptoms of Low Glutathione and How to Fix It Colair Beauty Glutathione, often dubbed the master antioxidant plays a crucial role in detoxification, immune function, and protecting our cells from oxidative stress. Here are some signs that your levels might be low: Persistent High glutathione levels simultaneously neutralize reactive oxygen Download Scientific Diagram Glutathione is the body's primary internal antioxidant, made using the amino acid cysteine, and it helps protect cells from oxidative stress. Beyond detoxification, research shows glutathione is involved in thyroid hormone metabolism, 9 Health Benefits of Glutathione Nineteen year follow up of a patient with severe glutathione synthetase deficiency Journal of Human Genetics