As a naturopathic doctor and a mom, Tylenol is a hard no in my house and I want to explain why. , , Acetaminophen (Tylenol) is processed through the liver, and in that process it can lower Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health Acetaminophen, also known as Tylenol, is used to help with pain & to reduce fever. However, taking too much acetaminophen can be harmful to the liver which filters out toxins & Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize Oxidative stress mediates end organ damage in a novel model of acetaminophen toxicity in Drosophila Scientific Reports