While it's been known that the essential function of #selenium was its incorporation as #selenocysteine into #selenoproteins (e.g. the enzyme glutathione peroxidase) now, Ingold et al. reveal the precise role of #selenolatebased # Reaction kinetics and targeting to cellular glutathione S transferase of the glutathione peroxidase mimetic PhSeZnCl and its d,l polylactide microparticle formulation ScienceDirect Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Cell Death & Disease International Journal of Molecular Medicine Role of iron, glutathione and lipid peroxidation in ferroptosis. Arrows Download Scientific Diagram Selective Small Molecule Activator of Patient Derived GPX4 Variant ACS Chemical Biology