Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Glutathione StransferasePi 1 protects cells from irradiationinduced death by inhibiting ferroptosis in pancreatic cancer Zhu 2024 The FASEB Journal Wiley Online Library Engineering nanomedicine for glutathione depletion augmented cancer therapy Chemical Society Reviews (RSC Publishing) Tumor targeted glutathione oxidation catalysis with ruthenium nanoreactors against hypoxic osteosarcoma Nature Communications Pan Cancer Metabolic Signature Predicts Co Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High Mesenchymal Cell State: Cell Metabolism Unveiling the Role of Glutathione S transferase Protein in Breast Cancer Drug Resistance: Insights into the Signaling Pathways and Therapeutic Implications ACS Pharmacology & Translational Science
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