Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential ScienceDirect Acetaminophen metabolism Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize Acetaminophen Toxicity in Children: Diagnosis, Clinical Assessment, and Treatment of Acute Overingestion Consultant360 Acetaminophen Pathway (toxic doses), Pharmacokinetics Acetaminophen causes neurodevelopmental injury in susceptible babies and children: no valid rationale for controversy