Frontiers The effect of major depressive disorder comorbidity on ischemia modified albumin levels, a marker of oxidative stress, and antioxidant defense system in patients with obsessive compulsive disorder Activity of energy, glutamate, and glutathione metabolism enzymes in blood cells of elderly patients with depression Glutathione: Benefits and Supplements Think You Know Glutathione? Think Again! Metagenics UK New research indicates a correlation between depression and reduced levels of antioxidants in the . Specifically, studies show that individuals with depression often exhibit lower levels of antioxidant enzymes like glutathione and Glutathione reductase Wikipedia