The GH IGF 1 axis in obesity: pathophysiology and therapeutic considerations Nature Reviews Endocrinology Everyone's calling GHK Cu a miracle peptide But let's separate marketing from mechanism. GHK Cu isn't magic. It's a signal. A signal that: Supports tissue repair Modulates inflammation Enhances collagen + GHK vs GHK Cu Without Copper, Basic Peptide Neurogan Health Synergy of GHKCu and hyaluronic acid on collagen IV upregulation via fibroblast and exvivo skin tests Jiang 2023 Journal of Cosmetic Dermatology Wiley Online Library The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin