History of Tylenol: Acetaminophen and Its Origins TikTok Tylenol depletes something called glutathione. Glutathione is a master antioxidant and your first line of protection against environmental toxins. It detoxifies and protects your cells. It protects your immune system and Tylenol Glutathione Kizer Wellness LLC Why you should avoid REGULAR acetaminophen use for babies and pregnancy 3 Little Plums Tylenol Avoid or Not to Avoid? Acetaminophen (Tylenol) can deplete glutathione, your body's most important detox antioxidant. This matters even more if your child has an MTHFR gene mutation, which Just say NO to Tylenol