Can You Donate Blood If You Smoke? Cannabis, Nicotine, and More Weed And Donating Blood: All You Need To Know Moose Labs Myth: You can't donate blood if you smoke or drink. Fact: Smoking or occasional drinking doesn't automatically disqualify you. But avoid alcohol for at least 24 hours before donating to We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating Smoking and High Blood Pressure: The Dangerous Link Can You Donate Blood or Plasma if You Use Cannabis?